American journal of physical medicine & rehabilitation
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Am J Phys Med Rehabil · Mar 2015
Review Meta AnalysisSystematic literature review of abobotulinumtoxinA in clinical trials for adult upper limb spasticity.
The aim of this study was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with upper limb spasticity (ULS). ⋯ On the basis of data extracted from 12 randomized clinical studies, a strong evidence base (9/12 studies) exists for the use of ABO to reduce ULS caused by stroke.