Surgical endoscopy
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Randomized Controlled Trial
Prevention of postoperative nausea and vomiting with a small dose of propofol alone and combined with dexamethasone in patients undergoing laparoscopic cholecystectomy: A prospective, randomized, double-blind study.
A small dose of propofol is directly antiemetic, and is effective for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy (LC). However, this regimen cannot entirely control PONV after LC. ⋯ Propofol 0.5 mg/kg combined with dexamethasone 8 mg is more effective than propofol alone for the prevention of PONV during the first 24 hours after anesthesia in patients undergoing LC.
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Randomized Controlled Trial
Heating of carbon dioxide during insufflation alters the peritoneal fibrinolytic response to laparoscopic surgery : A clinical trial.
Laparoscopic surgery is evolving rapidly. It involves the creation of a pneumoperitoneum, mostly using carbon dioxide. Cooling of the peritoneum, due to insufflation, might traumatize the peritoneum and disturb peritoneal fibrinolysis, important in peritoneal healing processes. The current study was performed to elucidate the effects of the temperature of insufflation gas on the peritoneal fibrinolytic response to laparoscopic surgery. ⋯ The temperature of carbon dioxide used for insufflation of the abdominal cavity affects peritoneal biology. Cooling of the peritoneum by unheated carbon dioxide causes increased peritoneal PAI-1 levels, important in peritoneal healing processes.