Canadian journal of gastroenterology = Journal canadien de gastroenterologie
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Can. J. Gastroenterol. · Jul 2013
HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.
Many patients referred for an elevated serum ferritin level <1000 µg⁄L are advised that they likely have iron overload and hemochromatosis. ⋯ Iron loading HFE mutations are unlikely to be the most common cause of an elevated serum ferritin level in patients with mild hyperferritinemia. Patients should be advised that there are many causes of an elevated serum ferritin level including iron overload.
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Can. J. Gastroenterol. · Jul 2013
Natural history and long-term outcomes of patients treated for early stage colorectal cancer.
The long-term natural history of early stage colon cancer and the outcome of long-term colonoscopic surveillance in routine specialist clinical practice after removal of the incident cancers have not been fully defined. In the present long-term evaluation up to 25 years, metachronous neoplasia, including both advanced adenomas and carcinomas, was defined. ⋯ Following removal of an incident symptomatic early stage colorectal cancer, the risk of later metachronous neoplasia persists for an extended period more than five years after removal of the incident colorectal cancer. Moreover, risk for late metachronous cancer appears to be predicted by the presence of multiple adenomas or advanced adenomas; most metachronous cancers in this cohort were detected using colonoscopy before onset of symptoms and at an early stage.
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Can. J. Gastroenterol. · Jun 2013
Open-access colonoscopy on Ontario: associated factors and quality.
Open-access (OA) colonoscopy may increase efficiency and decrease wait times; however, because the patient is seen for the first time at the endoscopy appointment, previous processes, such as information about the procedure, preparation and appropriate triage, may be suboptimal. ⋯ Rates of OA colonoscopy have increased substantially since 1997. Institution type was most strongly associated with OA colonoscopy. Colonoscopy completeness, a recognized quality indicator, does not appear to be compromised by OA colonoscopy.
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Can. J. Gastroenterol. · Apr 2013
Postoperative delirium in the intensive care unit predicts worse outcomes in liver transplant recipients.
Delirium is common in intensive care unit patients and is associated with worse outcome. ⋯ Intraoperative transfusion of packed red blood cells, pretransplantation renal replacement therapy and APACHE II score are predictors for the development of delirium in intensive care unit patients post-OLT and are associated with increased hospital lengths of stay and mortality.
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Can. J. Gastroenterol. · Dec 2012
A cohort study for derivation and validation of a clinical prediction scale for hospital-onset Clostridium difficile infection.
To develop and validate a clinical prediction scale for hospital-onset Clostridium difficile infection (CDI). ⋯ The authors developed and validated a simple clinical prediction scale for hospital-onset CDI. This score can be used for periodical evaluation of hospitalized patients for early initiation of contact precautions and empirical treatment once it is validated externally in a prospective manner.