Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Effect of preanesthetic intramuscular ranitidine on gastric acidity and volume in children.
To evaluate the effects of preanesthetic administration of intramuscular (IM) ranitidine on pH and volume of gastric contents in children. ⋯ Preanesthetic IM ranitidine 1 to 2 mg/kg resulted in a higher pH and lower volume of gastric fluid at the time of induction and in a higher pH during 3 hours of anesthesia. This therapy may be a useful adjunct to premedication for children who have a greater than normal risk of pulmonary aspiration during anesthesia.