Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Rapid oral anesthesia for awake intubation.
To determine whether sodium benzonatate (Tessalon Perles) can provide rapid, effective topical oral anesthesia in preparation for awake intubations. ⋯ The results of this study indicate that benzonatate capsules provide rapid and reliable oropharyngeal anesthesia in preparation for awake intubation. In addition, if excellent airway anesthesia is provided, awake intubations can be accomplished with minimal patient response and discomfort.
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Randomized Controlled Trial Comparative Study Clinical Trial
Neonatal acid-base status following general anesthesia for emergency abdominal delivery with halothane or isoflurane.
To determine whether halothane or isoflurane as anesthesia for emergency abdominal delivery is associated with better fetal acid-base parameters. ⋯ There is no difference in the frequency or severity of acidosis associated with isoflurane or halothane when used for general anesthesia for emergency abdominal delivery of a distressed fetus.
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Randomized Controlled Trial Clinical Trial
Flow increases with an enlarging intravenous catheter.
To determine the increase in flow of a hydratable enlarging intravenous (IV) catheter in anesthetized patients. ⋯ Flow through enlarging IV catheters placed in anesthetized patients increases after 1 hour. The percentage increase in flow is not as great as previously seen in vitro and may be due to skin, vein, and subcutaneous tissues preventing complete expansion.
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Randomized Controlled Trial Clinical Trial
Facilitation of rapid-sequence intubation with large-dose vecuronium with or without priming.
To determine the effect of priming on the intubation and onset times of vecuronium 0.3 mg/kg. ⋯ Seventy-five percent to 85% neuromuscular block of the adductor pollicis, required for atraumatic tracheal intubation, developed in 80 seconds or less when vecuronium 0.3 mg/kg was administered in divided doses and in 140 seconds or less when it was injected as a single bolus dose. Clinical duration of vecuronium 0.3 mg/kg is long and unpredictable, and reversal of residual neuromuscular block may require larger doses of anticholinesterases. It is recommended that an intubating dose of vecuronium 0.3 mg/kg be used only in patients undergoing long surgical procedures that require prolonged postanesthetic mechanical ventilation.
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Randomized Controlled Trial Comparative Study Clinical Trial
Mivacurium as an alternative to succinylcholine during outpatient laparoscopy.
To compare (1) the adequacy of conditions for tracheal intubation; (2) the onset, depth, clinically effective duration, and recovery profile; and (3) adverse effects associated with mivacurium as an alternative to succinylcholine during general (endotracheal) anesthesia for outpatient laparoscopy. ⋯ Mivacurium 0.15 mg/kg given intravenously provided good to excellent conditions for tracheal intubation in 2 to 3 minutes. This dose provided a clinically effective duration of action of 20 to 25 minutes, and the residual blockade was readily reversible with neostigmine. Mivacurium did not, however, offer any apparent advantage over succinylcholine in this outpatient population.