Journal of clinical anesthesia
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To assess the complications associated with the aspiration of sucralfate. ⋯ Acute complications associated with aspiration of sucralfate have been identified. In the laboratory setting, simulated aspiration of sucralfate led to acute lung injury.
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To evaluate the independent effects of opioid induction and paralysis on changes in mixed venous oxygen saturation (SvO2). ⋯ Opioid anesthesia, not paralysis, increases SvO2. Most of the decrease in VO2 occurs from anesthesia, not paralysis. The direct relationship between CI and SvO2 no longer holds upon induction of anesthesia. Parallel changes in CI cannot be inferred based on SvO2 alone.
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Randomized Controlled Trial Clinical Trial
The effect of d-tubocurarine priming on an ED95 dose of vecuronium bromide.
To examine how priming with ED10 d-tubocurarine prior to the administration of ED95 vecuronium bromide affects onset and duration of neuromuscular blockade. ⋯ These results indicate that crossover dosing of nondepolarizing muscle relaxants may have synergistic effects. Priming with ED10 d-tubocurarine prior to an ED95 dose of vecuronium shortens the time to 80% T1 depression and produces satisfactory intubating conditions at 90 seconds, without prolonging the duration of the Therefore, d-tubocurarine is an attractive drug for priming vecuronium in short operative procedures that require muscle relaxation.
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Randomized Controlled Trial Clinical Trial
Intravenous ketorolac as an adjuvant to pediatric patient-controlled analgesia with morphine.
To assess the effects of a single intraoperative dose of intravenous (i.v.) ketorolac on postoperative opioid dose requirements, quality of analgesia as assessed by the patient, and frequency of opioid-related side effects during pediatric patient-controlled analgesia (PCA) with morphine. ⋯ A single intraoperative dose of i.v. ketorolac appears to be opioid dose sharing, to provide superior analgesia, and to decrease the frequency of urinary retention during the first 12 hours of postoperative pediatric PCA with morphine.