Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Serum and urine inorganic fluoride levels following prolonged low-dose sevoflurane anesthesia combined with epidural block.
To determine whether serum and urine inorganic fluoride levels with prolonged (more than 7 hours) low-dose (0.8 to 2.0 vol %) sevoflurane anesthesia plus epidural anesthesia were increased as compared with isoflurane anesthesia plus epidural anesthesia. To measure the urine tubular enzymes N-acetyl-beta-glucosaminidase (NAG), alpha 1-microglobulin (alpha 1-M), and beta 2-microglobulin (beta 2-M) for renal tubular injury in both groups. ⋯ There was no increase in urinary enzymes, which are indicators of tubular injury, specific to sevoflurane. There was no postoperative renal dysfunction, as indicated by unchanged serum creatinine and blood urea nitrogen levels.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effects of subcutaneous verapamil on the duration of local anesthetic blockade.
To determine whether a subcutaneous injection of verapamil will provide local anesthesia and whether a mixture of lidocaine and verapamil will prolong the anesthetic effect of lidocaine alone. ⋯ Verapamil injected subcutaneously provides a degree of local anesthesia. However, this effect is hampered by a local reaction at the injection site and a short duration of action. The mixture of lidocaine and verapamil provides a shorter duration of action than does lidocaine alone.
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Randomized Controlled Trial Clinical Trial
Evaluation of the efficacy of a forced-air warmer (Bair Hugger) during spinal surgery in children.
To evaluate the efficacy of a forced-air warmer during spinal surgery for correction of scoliosis in children. ⋯ The forced-air warmer (Bair Hugger) is effective during spinal surgery, although only about 20% of body surface area can be covered.