Journal of clinical anesthesia
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Comparative Study Clinical Trial
Comparative recovery of 50-Hz and 100-Hz posttetanic twitch following profound neuromuscular block.
To determine if posttetanic twitch following 100-Hz tetanic stimulation enables titration of a nondepolarizing relaxant infusion to a greater depth of block than that achieved with posttetanic twitch following 50 Hz. ⋯ Posttetanic twitch following 100-Hz tetanic stimulation enables titration of a vecuronium infusion to a greater depth of block than posttetanic twitch following 50-Hz tetanic stimulation. The present findings should enable more effective titration of this relaxant, thereby reducing the likelihood of unwanted patient movement or unduly prolonged recovery due to relaxant overdosing.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of epidural morphine and oxycodone for pain after abdominal surgery.
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Sarcoidosis, a rare multisystem disease, often occurs in women of childbearing age. The disease, which may be improved or exacerbated by pregnancy, presents unique considerations to the anesthesiologist. These considerations are illustrated by the case presented here of complicated sarcoidosis in a parturient who underwent cesarean section.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Etomidate and thiopental-based anesthetic induction: comparisons between different titrated levels of electrophysiologic cortical depression and response to laryngoscopy.
To determine whether etomidate-based induction can provide better hemodynamics than a standard thiopental sodium-based anesthetic induction. ⋯ Etomidate-based anesthetic induction, titrated to EEG burst suppression, produced stable hemodynamics during laryngoscopy and intubation as compared with lower dose, more "classic" inductions with etomidate or thiopental.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postoperative analgesia using a low-dose, oral-transdermal clonidine combination: lack of clinical efficacy.
To determine if a lower than previously reported oral-transdermal clonidine regimen could reduce postoperative morphine requirements without producing systemic side effects. ⋯ The low-dose oral-transdermal clonidine regimen evaluated failed to reduce postoperative morphine requirements, although patients who received clonidine were still at risk for developing hypotension.