Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Postoperative analgesia with parenteral opioids: does continuous delivery utilizing a transdermal opioid preparation affect analgesic efficacy or patient safety?
To compare, in patients who underwent major orthopedic surgical procedures, the efficacy of intravenous (IV) patient-controlled analgesia (PCA) with morphine combined with continuous administration of two doses of fentanyl or placebo via transdermal therapeutic system with fentanyl (TTSF) patches. ⋯ There is no significant advantage to the routine use of continuous transdermal opioid delivery in patients receiving IV PCA after major orthopedic surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Pulse oximeter performance during desaturation and resaturation: a comparison of seven models.
To compare pulse oximeter performance during induced hypoxemia. ⋯ Most models of oximeters tested performed well when hemoglobin oxygen saturation was high, but all were inaccurate when SaO2 was approximately 75%. During induced hypoxemia, there were significant differences in the response times of oximeters tested, with no model demonstrably superior to others in all measures of performance.
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Venous air embolism (VAE) can be a lethal complication of surgical procedures, during which (1) venous pressure at the site of surgery is subatmospheric or (2) gas is forced under pressure into a body cavity. Though classically associated with neurosurgery, VAE is also a potential complication of laparoscopic, pelvic, and orthopedic procedures. It is, therefore, essential for the practicing anesthesiologist to recognize and treat venous air entrainment. An in-depth review of the pathophysiology, clinical presentation, detection, prevention, and treatment of VAE is presented.
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Randomized Controlled Trial Comparative Study Clinical Trial
Priming with rocuronium accelerates the onset of neuromuscular blockade.
To investigate the effects of priming rocuronium on the time course of neuromuscular blockade. ⋯ Priming rocuronium decreased the onset times and thus, the intubating times without increasing the clinical duration of action or recovery index.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postthyroidectomy analgesia: morphine, buprenorphine, or bupivacaine?
To compare three analgesic regimens for pain relief after thyroidectomy. ⋯ The administration of sublingual buprenorphine after thyroidectomy provides better analgesia than small doses of oral controlled-release morphine or than 0.25% bupivacaine wound infiltration at the end of surgery.