Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Effects of tramadol and meperidine on respiration, plasma catecholamine concentrations, and hemodynamics.
To evaluate the effects of high analgesic doses of tramadol and meperidine on respiration, plasma catecholamine concentrations, and hemodynamic parameters. ⋯ Tramadol exhibited a minimal effect on respiration and breathing pattern in healthy volunteers. The respiratory effects of meperidine bolus were predictable with decreasing tidal volume and pulse oxygen saturation. In contrast, during meperidine infusion, adequate respiration was preserved despite the large amount of meperidine infused.
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Randomized Controlled Trial Clinical Trial
Xenon suppresses the hypnotic arousal in response to surgical stimulation.
To evaluate the suppressive effects of xenon (Xe) on hypnotic arousal at skin incision. ⋯ Unlike N2O, Xe was able to suppress hypnotic arousal in response to surgical stimulation when administered with sevoflurane.
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Randomized Controlled Trial Comparative Study Clinical Trial
The optimal effective concentration of lidocaine to reduce pain on injection of propofol.
To determine the optimal concentration of lidocaine that reduces pain on injection of a propofol-lidocaine mixture. ⋯ The optimal effective concentration of lidocaine, which decreased the incidence of pain caused by propofol injection, was 0.1% in the currently studied population.
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Randomized Controlled Trial Clinical Trial
Preoperative pulse wave velocity fails to predict hemodynamic responses to anesthesia and to surgical stimulation.
To determine whether pulse wave velocity (PWV), which is a useful indicator of cardiovascular disease, can predict the hemodynamic responses to anesthesia and surgical stimulation in surgical patients. ⋯ Preoperative PWV fails to predict hemodynamic responses to anesthesia and to surgical stimulation.
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Randomized Controlled Trial Comparative Study Clinical Trial
Insertion of the cuffed oropharyngeal airway (COPA) with propofol or sevoflurane in adults.
To compare the respiratory depressant effects of propofol and sevoflurane used to facilitate the placement of the cuffed oropharyngeal airway (COPA), and to evaluate the effectiveness of the COPA in supporting positive pressure ventilation during anesthetic-induced apnea. ⋯ Propofol and sevoflurane are equally effective in facilitating the placement of the COPA. However, propofol often induces apnea, which is complicated by a less effective seal of the airway by the COPA against positive pressures. Because sevoflurane induction allows spontaneous respiration to continue and provides an adequate pharyngeal seal immediately following the placement of the COPA, it may be advantageous when apnea is not desired.