Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Antagonism of profound cisatracurium and rocuronium block: the role of objective assessment of neuromuscular function.
The purpose of this study is to determine the incidence of significant (train-of-four [TOF] ratio <0.70), but clinically undetectable (TOF ratio >0.40), residual neuromuscular block after neostigmine antagonism of profound cisatracurium (CIS) or rocuronium (ROC) block. ⋯ Most clinicians cannot detect tactile fade once the TOF ratio exceeds 0.40. When reversing profound block, an objective monitor of neuromuscular function is required if the extent of residual block is to be assessed with any confidence.
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Randomized Controlled Trial Clinical Trial
Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache.
To investigate the effects of different doses of oral caffeine-paracetamol combinations in postdural puncture headache (PDPH) prophylaxis. ⋯ Prophylactic administration of paracetamol-caffeine combinations at the stated doses does not prevent PDPH.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of the effects of propofol and midazolam on the cardiovascular autonomic nervous system during combined spinal and epidural anesthesia.
To investigate the effect of propofol and midazolam on cardiac autonomic nervous system (CANS) activity during combined spinal-epidural anesthesia. ⋯ Propofol was more potent than midazolam in causing CANS activity to be sympatholytic during combined spinal and epidural anesthesia and which was correlated with age only with propofol.
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Randomized Controlled Trial Comparative Study Clinical Trial
Recovery and cognitive function after fentanyl or remifentanil administration for carotid endarterectomy.
To compare recovery and restoration of cognitive function after fentanyl-propofol or remifentanil-propofol anesthesia administration in patients undergoing carotid endarterectomy. ⋯ Although intraoperative hemodynamics were better preserved and immediate recovery was more rapid with remifentanil, overall postoperative recovery and restoration of cognitive functions as well as postoperative pain intensity seem to be similar for patients receiving remifentanil and for those receiving fentanyl combined with propofol for carotid endarterectomy operations.
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Randomized Controlled Trial Clinical Trial
Effects of atrial natriuretic peptide at a low dose on water and electrolyte metabolism during general anesthesia.
To assess the hemodynamic, renal, and endocrine effects of small continuous doses of atrial natriuretic peptide (ANP) in patients anesthetized with sevoflurane for gastrectomy. ⋯ Continuous intravenous infusion of ANP at 0.05 microg/kg/min during gastrectomy was associated with greater water and electrolyte excretion unaccompanied by changes in potentially interacting hormones. Low-dose infusion may be particularly safe and useful for controlling water and electrolyte metabolism intraoperatively.