Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study
Comparison of buccal and intramuscular dexmedetomidine premedication for arthroscopic knee surgery.
To compare the sedative, anxiolytic, analgesic, hemodynamic, and respiratory effects of buccal dexmedetomidine with intramuscular (IM) dexmedetomidine for premedication in patients undergoing arthroscopic knee surgery during spinal anesthesia. ⋯ Buccal dexmedetomidine for premedication in arthroscopic knee surgery provided equal levels of sedation and anxiolysis, and more evident analgesia compared with IM dexmedetomidine.
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Randomized Controlled Trial
Effects of mannitol in the prevention of lipid peroxidation during liver resection with hepatic vascular exclusion.
To examine the efficacy of mannitol in the prevention of lipid peroxidation during major liver resections performed during hepatic inflow occlusion. ⋯ Mannitol has an antioxidant activity, but we were unable to confirm a positive impact on the postoperative clinical course.
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Randomized Controlled Trial Comparative Study
The effect of injection of two vs 10 mL saline on the subsequent spread and quality of epidural analgesia in parturients.
To determine whether two vs 10 mL of saline injected into the epidural space affects the subsequent spread and quality of epidural analgesia in parturients. ⋯ 10 mL saline was associated with a higher total number of dermatomes blocked for both cold and pinprick sensation than the two mL saline. However, the pain relief was adequate in both groups, and two mL saline was as effective as the 10 mL in the ease of catheter insertion and prevention of intravascular cannulation.
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Randomized Controlled Trial
Improved postoperative analgesia with coadministration of preoperative epidural ketamine and midazolam.
To assess postoperative pain regulation and pharmacokinetic effects of preoperative administration of ketamine and midazolam. ⋯ Preoperative epidural coadministration of a low dose of ketamine with midazolam is more effective in relieving postoperative pain than using ketamine alone. In addition, epidural midazolam prolongs the elimination of ketamine.
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Randomized Controlled Trial Comparative Study
Extubation time, hemodynamic stability, and postoperative pain control in patients undergoing coronary artery bypass surgery: an evaluation of fentanyl, remifentanil, and nonsteroidal antiinflammatory drugs with propofol for perioperative and postoperative management.
To compare three anesthetic strategies with respect to the time of extubation after coronary artery bypass graft (CABG) surgery and to assess patient satisfaction with the procedure. ⋯ Intravenous propofol with bolus doses of IV fentanyl intraoperatively in combination with postoperative nonsteroidal antiinflammatory drugs had the best recovery profile in patients undergoing primary CABG than did the other two regimens studied.