Journal of clinical anesthesia
-
Randomized Controlled Trial
Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation.
To evaluate the effect of preadministration of flurbiprofen on the plasma concentrations of prostaglandin E2 (PGE2) and postoperative pain. ⋯ Preadministration of flurbiprofen suppresses the local production of PGE2 during tourniquet ischemia, resulting in reduced early postoperative pain in patients undergoing knee surgery.
-
Review Historical Article
Nitrous or nitric? Same difference. Molecular formulas in the 1840s.
The molecular formulas given by James Y. Simpson for nitrous oxide, diethyl ether, and chloroform are difficult to interpret today. ⋯ The nitrous oxide formula was incorrect owing to confusion with Dalton's nitrous gas, now termed nitric oxide. The Simpson formulas illustrate that inhaled anesthesia arrived at the time of a cusp in the history of chemistry.
-
Randomized Controlled Trial Comparative Study
Clinical comparisons between GlideScope video laryngoscope and Trachlight in simulated cervical spine instability.
To compare the time taken for tracheal intubation, hemodynamic changes, and perioperative morbidities between the GlideScope (GS) video laryngoscope and the Trachlight (TL) with manual inline stabilization. ⋯ Trachlight offers a faster intubation and a milder hemodynamic response than GS.
-
Controlled Clinical Trial
Relation between middle ear pressure changes and postoperative nausea and vomiting in pediatric strabismus surgery.
To investigate the effects of tympanometric changes on the frequency of postoperative nausea and vomiting (PONV). ⋯ Gradient, compliance, volume, and pressure changes in middle ears were not found to be related to the frequency of nausea and vomiting after strabismus surgery.
-
Currently used methods of sedation for fiberoptic intubation such as benzodiazepines, propofol, or opioids have their limitations. Dexmedetomidine (DEX) is a selective alpha-2 adrenergic agonist that has been used clinically for its sympatholytic, analgesic, and sedative properties. We report on 4 patients with particularly difficult airways who underwent successful awake fiberoptic intubation with DEX. Dexmedetomidine was used to provide a moderate level of conscious sedation without causing respiratory distress or hemodynamic instability during fiberoptic intubation.