Journal of clinical anesthesia
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Randomized Controlled Trial
Evaluation of low-dose propofol preadministration to attenuate vascular pain during induction of anesthesia.
To determine whether a small dose of propofol before induction decreases pain with injection using two different formulas of propofol-10% long-chain triglycerides (LCT) and medium-chain triglycerides (MCT) and LCT. ⋯ Long-chain triglyceride and LCT/MCT propofol, 0.1 mg/kg administration before induction, resulted in attenuated pain at an induction dose of propofol.
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Comparative Study
Vein occlusion by upper versus forearm tourniquets in humans.
To determine the optimal location for a tourniquet applied to the arm during cannulation of a hand vein. ⋯ A tourniquet on the forearm effectively distends hand veins and does so more quickly than a tourniquet on the upper arm.
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To determine whether a new Sonoclot-based, aprotinin-insensitive activated clotting time (aiACT) assay yields stable results over a broad range of aprotinin concentrations. ⋯ Aprotinin (160, 320, and 500 KIU/mL) significantly prolongs the ACT value with celite and kaolin activators but not with the aprotinin-insensitive activator.
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Fetal oxygen saturation (FSpo(2)) is an emerging technology for intrapartum fetal monitoring. We monitored FSpo(2) before and after combined spinal-epidural analgesia in 8 laboring women requesting neuraxial analgesia. ⋯ Fetal oxygen saturation at baseline and after analgesia was 53% +/- 9% and 51% +/- 8%, respectively. We observed no significant FHR changes or any fetal bradycardia following combined spinal-epidural analgesia.
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Case Reports
Malignant hyperthermia associated with diabetic hyperosmolar hyperglycemic nonketotic state in a young man.
Malignant hyperthermia (MH) is a rare complication that often leads to adverse outcomes, catastrophic events, or death. Although various risk factors and underlying diseases are associated with this condition, unusual presentations may be missed. ⋯ We present a case of an MH-like syndrome in a young Hispanic man who was diagnosed with new-onset diabetes mellitus and hyperglycemic hyperosmolar nonketotic state. The patient had no obvious risk or precipitating factors for MH.