Journal of clinical anesthesia
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Randomized Controlled Trial
Esmolol pretreatment reduces the frequency and severity of pain on injection of rocuronium.
To determine the effect of esmolol on the frequency and severity of pain and withdrawal reactions after injection of rocuronium and to compare it with lidocaine and placebo. ⋯ Esmolol, like lidocaine, reduces the frequency of pain and withdrawal reaction associated with rocuronium injection.
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Randomized Controlled Trial
Neutralized rocuronium (pH 7.4) before administration prevents injection pain in awake patients: a randomized prospective trial.
To determine (1) the amount of 8.4% sodium bicarbonate (NaHCO(3)) to adjust the pH of rocuronium to 7.4 (neutralization), (2) to show whether neutralizing the pH of rocuronium can prevent pain, and (3) to confirm that rocuronium mixed with NaHCO(3) does not change the physical property and efficacy of rocuronium. ⋯ Rocuronium neutralized with NaHCO(3) prevents intravenous injection pain. The physical and pharmacologic properties of rocuronium mixed with NaHCO(3) immediately before administration are not altered.
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Randomized Controlled Trial
The effect of stimulating versus nonstimulating catheters for continuous interscalene plexus blocks in short-term pain management.
To investigate whether placement, and use of stimulating catheters for interscalene brachial plexus blocks improves short-term postoperative analgesia. ⋯ Stimulating catheters for interscalene plexus blocks improve postoperative analgesia at rest in patients undergoing shoulder surgery.
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Comparative Study
Vein occlusion by upper versus forearm tourniquets in humans.
To determine the optimal location for a tourniquet applied to the arm during cannulation of a hand vein. ⋯ A tourniquet on the forearm effectively distends hand veins and does so more quickly than a tourniquet on the upper arm.
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Case Reports
Malignant hyperthermia associated with diabetic hyperosmolar hyperglycemic nonketotic state in a young man.
Malignant hyperthermia (MH) is a rare complication that often leads to adverse outcomes, catastrophic events, or death. Although various risk factors and underlying diseases are associated with this condition, unusual presentations may be missed. ⋯ We present a case of an MH-like syndrome in a young Hispanic man who was diagnosed with new-onset diabetes mellitus and hyperglycemic hyperosmolar nonketotic state. The patient had no obvious risk or precipitating factors for MH.