Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study
Parecoxib sodium administered over several days reduces pain after gynecologic surgery via laparotomy.
To assess the analgesic efficacy of a multidose, multiday regimen of intravenous (IV) parecoxib sodium (parecoxib). ⋯ Multidose parecoxib was well tolerated over several days and provided improved pain control after gynecologic surgery.
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Randomized Controlled Trial
Mode of ventilation during cardiopulmonary bypass does not affect immediate postbypass oxygenation in pediatric cardiac patients.
To investigate the impact of different modes of ventilation during cardiopulmonary bypass (CPB) on immediate postbypass oxygenation in pediatric cardiac surgery. ⋯ Mode of ventilation during CPB did not affect immediate postbypass oxygenation.
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Randomized Controlled Trial
Evaluation of low-dose propofol preadministration to attenuate vascular pain during induction of anesthesia.
To determine whether a small dose of propofol before induction decreases pain with injection using two different formulas of propofol-10% long-chain triglycerides (LCT) and medium-chain triglycerides (MCT) and LCT. ⋯ Long-chain triglyceride and LCT/MCT propofol, 0.1 mg/kg administration before induction, resulted in attenuated pain at an induction dose of propofol.
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To determine whether a new Sonoclot-based, aprotinin-insensitive activated clotting time (aiACT) assay yields stable results over a broad range of aprotinin concentrations. ⋯ Aprotinin (160, 320, and 500 KIU/mL) significantly prolongs the ACT value with celite and kaolin activators but not with the aprotinin-insensitive activator.