Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study
Parecoxib sodium administered over several days reduces pain after gynecologic surgery via laparotomy.
To assess the analgesic efficacy of a multidose, multiday regimen of intravenous (IV) parecoxib sodium (parecoxib). ⋯ Multidose parecoxib was well tolerated over several days and provided improved pain control after gynecologic surgery.
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Randomized Controlled Trial
Esmolol pretreatment reduces the frequency and severity of pain on injection of rocuronium.
To determine the effect of esmolol on the frequency and severity of pain and withdrawal reactions after injection of rocuronium and to compare it with lidocaine and placebo. ⋯ Esmolol, like lidocaine, reduces the frequency of pain and withdrawal reaction associated with rocuronium injection.
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Randomized Controlled Trial
Neutralized rocuronium (pH 7.4) before administration prevents injection pain in awake patients: a randomized prospective trial.
To determine (1) the amount of 8.4% sodium bicarbonate (NaHCO(3)) to adjust the pH of rocuronium to 7.4 (neutralization), (2) to show whether neutralizing the pH of rocuronium can prevent pain, and (3) to confirm that rocuronium mixed with NaHCO(3) does not change the physical property and efficacy of rocuronium. ⋯ Rocuronium neutralized with NaHCO(3) prevents intravenous injection pain. The physical and pharmacologic properties of rocuronium mixed with NaHCO(3) immediately before administration are not altered.
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Randomized Controlled Trial
Mode of ventilation during cardiopulmonary bypass does not affect immediate postbypass oxygenation in pediatric cardiac patients.
To investigate the impact of different modes of ventilation during cardiopulmonary bypass (CPB) on immediate postbypass oxygenation in pediatric cardiac surgery. ⋯ Mode of ventilation during CPB did not affect immediate postbypass oxygenation.