Journal of clinical anesthesia
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Randomized Controlled Trial
Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial.
To assess the effect of different intraoperative blood pressure targets on the development of POCD and test the feasibility of a larger trial. ⋯ Intraoperative hypotension did not correlate with postoperative cognitive dysfunction or delirium occurrence in elderly patients undergoing general anesthesia for non-cardiac surgery. A multicenter randomized controlled trial is needed in order to confirm the effect of intraoperative blood pressure on the development of POCD.
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Observational Study
Minute ventilation assessment in the PACU is useful to predict postoperative respiratory depression following discharge to the floor: A prospective cohort study.
Reliably identifying patients at risk for postoperative respiratory depression (RD) remains an unmet need. We hypothesized that defined low minute ventilation events (LMVe) near the end of the post-anesthesia care unit (PACU) stay identifies patients at RD risk on the general hospital floor (GHF). ⋯ Minute ventilation assessment in the PACU as described in this study can be useful to identify patients at risk for postoperative respiratory depression.