Journal of clinical anesthesia
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Clinical Trial Controlled Clinical Trial
Echocardiographic evaluation of global left ventricular function during high thoracic epidural anesthesia.
To assess the effects of high thoracic epidural anesthesia on left ventricular (LV) diastolic filling and systolic function in patients without heart disease. ⋯ High thoracic epidural anesthesia causes a decrease in CO without changing LV ejection and diastolic filling performance in healthy subjects.
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Comparative Study Clinical Trial Controlled Clinical Trial
Superiority of multi-orifice over single-orifice epidural catheters for labor analgesia and cesarean delivery.
To investigate whether a change from a single-orifice to multi-orifice catheter could reduce the incidence of inadequate epidural blocks requiring replacement of the epidural catheter in obstetric patients. ⋯ The multi-orifice design offers significant advantages over the single-orifice type for obstetricepidural analgesia.
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To obtain data about the safety and efficacy of the size 5 laryngeal mask airway (LMA), which is a scaled-up version of the size 4 and is generally recommended for patients over 90 kg, for positive pressure ventilation (PPV), ease of insertion, oropharyngeal and gastric insufflation pressures, fiberoptic positioning, and complication rates. ⋯ Positive pressure ventilation with the size 5 LMA is safe and effective with a low failure/problem rate using tidal volumes of 8 to 10 ml/kg, even in those patients who are moderately obese. The device is suitable for patients weighing under 90 kg in whom the seal with the size 4 is inadequate.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Etomidate and thiopental-based anesthetic induction: comparisons between different titrated levels of electrophysiologic cortical depression and response to laryngoscopy.
To determine whether etomidate-based induction can provide better hemodynamics than a standard thiopental sodium-based anesthetic induction. ⋯ Etomidate-based anesthetic induction, titrated to EEG burst suppression, produced stable hemodynamics during laryngoscopy and intubation as compared with lower dose, more "classic" inductions with etomidate or thiopental.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postoperative analgesia using a low-dose, oral-transdermal clonidine combination: lack of clinical efficacy.
To determine if a lower than previously reported oral-transdermal clonidine regimen could reduce postoperative morphine requirements without producing systemic side effects. ⋯ The low-dose oral-transdermal clonidine regimen evaluated failed to reduce postoperative morphine requirements, although patients who received clonidine were still at risk for developing hypotension.