Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Xenon suppresses the hypnotic arousal in response to surgical stimulation.
To evaluate the suppressive effects of xenon (Xe) on hypnotic arousal at skin incision. ⋯ Unlike N2O, Xe was able to suppress hypnotic arousal in response to surgical stimulation when administered with sevoflurane.
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Randomized Controlled Trial Comparative Study Clinical Trial
Insertion of the cuffed oropharyngeal airway (COPA) with propofol or sevoflurane in adults.
To compare the respiratory depressant effects of propofol and sevoflurane used to facilitate the placement of the cuffed oropharyngeal airway (COPA), and to evaluate the effectiveness of the COPA in supporting positive pressure ventilation during anesthetic-induced apnea. ⋯ Propofol and sevoflurane are equally effective in facilitating the placement of the COPA. However, propofol often induces apnea, which is complicated by a less effective seal of the airway by the COPA against positive pressures. Because sevoflurane induction allows spontaneous respiration to continue and provides an adequate pharyngeal seal immediately following the placement of the COPA, it may be advantageous when apnea is not desired.
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Randomized Controlled Trial Clinical Trial
Optimal length and angle of a new lightwand device (Trachlight).
To investigate the effects of angle and length of the Trachlight lightwand and the effect of obesity on transillumination of the neck and difficulty of intubation. ⋯ To increase the success rate of tracheal intubation using the lightwand, the lightwand should be bent in 40 degrees to 60 degrees, with the extrusion of 1 to 2 cm from the tracheal tube. For obese patients with body weight > or = 120% of the standard, the lightwand was not useful.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Comparison of renal function following anesthesia with low-flow sevoflurane and isoflurane.
To evaluate postoperative renal function after patients were administered sevoflurane under conditions designed to generate high concentrations of compound A. ⋯ There were no statistically significant differences in the renal effects of sevoflurane or isoflurane in surgical patients undergoing low-flow anesthesia for up to 8 hours. Low-flow sevoflurane anesthesia under clinical conditions expected to produce high levels of compound A appears as safe as low-flow isoflurane anesthesia.
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Randomized Controlled Trial Clinical Trial
A comparison of the onset and clinical duration of high doses of cisatracurium and rocuronium.
To determine the onset and clinical duration of cisatracurium and rocuronium in equipotent doses in balanced opioid/isoflurane anesthesia. ⋯ With equipotent intubating doses of rocuronium and cisatracurium, rocuronium produces a more rapid onset of muscle relaxation. The data suggest a tendency toward more rapid clinical recovery of cisatracurium compared to equipotent doses of rocuronium, although these differences were not statistically significant.