Gynecologic oncology
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Gynecologic oncology · Jul 2007
Randomized Controlled Trial Multicenter StudyPrognostic factors for complete debulking in advanced ovarian cancer and its impact on survival. An exploratory analysis of a prospectively randomized phase III study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR).
No residual tumor as result of primary surgery in advanced ovarian cancer is known as one of the most important prognostic factors. ⋯ Post-operative residual tumor is one of the most important independent prognostic factor for survival. Our results suggest an advantage for aggressive primary surgery and complete debulking. This surgical goal was achieved more often in experienced centers.