Journal of anesthesia
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Journal of anesthesia · Mar 1994
Clonidine premedication for sevoflurane anesthesia in upper abdominal surgery.
The effects of clonidine as a preanesthetic medication were compared with diazepam on clinical courses of sevoflurane anesthesia in 22 patients undergoing upper abdominal surgery. The patients were divided into two groups of 11 patients each according to preanesthetic medication: atropine 0.5 mg i.m. plus clonidine 0.3 mg p.o., or atropine 0.5 mg i.m. plus diazepam 10 mg p.o. 60-90 min prior to induction of anesthesia. Anesthesia was induced with fentanyl and thiopental, and was maintained with sevoflurane, 0.5%-1.5%, nitrous oxide and oxygen, supplemented with fentanyl, 0.5 μg·kg-1·hr-1. ⋯ Pain score after extubation was higher in the diazepam group than in the clonidine group. The time when patients responded to verbal command after discontinuation of anesthetics was similar in both groups. Therefore, clonidine pretreatment was useful for sevoflurane anesthesia in upper abdominal surgery.
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Journal of anesthesia · Mar 1994
Effects of a forced-air system (Bair Hugger, OR-type) on intraoperative temperature in patients with open abdominal surgery.
Intraoperative hypothermia is difficult to avoid and may present a significant clinical risk during the early postoperative phase. We evaluated a forced-air system [Bair Hugger, OR-type (BH)] for warming intraoperative patients with open abdominal surgery. Twenty patients received BH warming [BH(+) group] and another 20 patients, who served as controls, did not [BH(-) group]. ⋯ Rectal and fingertip temperatures in the BH(+) group were significantly higher than those in the BH(-) group, and central-peripheral temperature gradients in the BH(+) group were significantly smaller than those in the BH(-) group during the study, except at 180 min. No shivering occurred in either group. Therefore, BH is an effective warming device during open abdominal surgery.
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The stability of enflurane in soda lime was examined. A product of enflurane decomposition was detected after the reaction of enflurane with soda lime, but not in the absence of soda lime. ⋯ The same decomposition product was produced by the reaction of enflurane with potassium, sodium, or calcium hydroxides, and it was also detected in the gas phase at a maximum concentration of 1.29 ppm at 420 min after 5% enflurane circulated with 200 ml/min carbon dioxide gas in a closed anesthesia circle system with a soda lime canister and a model lung. We concluded that enflurane was decomposed to 1-chloro-1,2-difluorovinyl difluoromethyl ether by soda lime.