Journal of anesthesia
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical TrialEfficacy of prophylactic intravenous granisetron in postoperative emesis in adults.
This randomized, double-blind, placebo-controlled trial evaluated the efficacy, safety, and optimal dose of granisetron in the prophylactic control of postoperative nausea and vomiting in patients undergoing gynecologic surgery or cholecystectomy. ⋯ Granisetron is well-tolerated and more effective than placebo in the prophylactic control of nausea and vomiting after surgery. This study suggests that the optimum dose of granisetron is 1 mg.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical Trial Controlled Clinical TrialRopivacaine produces sensory blockade in the lumbar sacral region more frequently than mepivacaine in lower thoracic epidural anesthesia.
The first sacral nerve has the largest diameter among the spinal nerves and is resistant to local anesthetics. Ropivacaine is a newly developed local anesthetic. There is a possibility that a difference in chemical properties between ropivacaine and other local anesthetics produces a difference in the blockade of the S1 dermatome by lower thoracic epidural anesthesia. Mepivacaine, 2%, is frequently used for epidural anesthesia and produces a level of blockade similar to that of bupivacaine, 0.5%. The purpose of this study was to examine the sensory blockade in the sacral region induced by ropivacaine with that induced by mepivacaine administered in the lower thoracic epidural space. ⋯ Ropivacaine, 1%, administered in the lower thoracic epidural space, induces sensory blockade to cold and pinprick in the S1 dermatome more frequently than 2% mepivacaine.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison between a disposable and an electronic PCA device for labor epidural analgesia.
The aims of the present study were (1) to investigate if a disposable patient-controlled analgesia (PCA) device can be used for labor analgesia and (2) to evaluate the device by midwives and parturients. ⋯ The present results imply that the disposable PCA device can be an alternative to the electronic PCA device for labor analgesia.
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Journal of anesthesia · Jan 2004
Clinical Trial Controlled Clinical TrialLaryngotracheal application of lidocaine spray increases the incidence of postoperative sore throat after total intravenous anesthesia.
To determine the effect of laryngotracheal application of different doses of lidocaine spray on postoperative sore throat and hoarseness, we evaluated the incidence and severity of these complications in 168 ASA I-III patients aged 15-92 years in a placebo-controlled study. ⋯ We recommend that applications of lidocaine spray to the laryngotracheal area should be avoided to help eliminate unnecessary postoperative sore throat, thereby leading to improvement in patient satisfaction.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of postoperative sore throat after use of laryngeal mask airway and tracheal tube.
We compared the degree of postoperative sore throat (PST) after use of a laryngeal mask airway (LMA; by two insertion techniques) and a tracheal tube (TT) in adult patients. ⋯ In the conditions of our study, LMAs inserted with the cuff either fully inflated or deflated worsened PST compared with TTs.