Journal of anesthesia
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical TrialIsoflurane increases, but sevoflurane decreases blood concentrations of melatonin in women.
The blood concentrations of melatonin are elevated by stress-induced sympathetic nerve excitation and are affected by some anesthetics. Isoflurane has an effect to increase sympathetic nerve activity when compared with sevoflurane. This study was performed to investigate the effects of these two anesthetics on the blood concentrations of melatonin. ⋯ We obtained blood samples before and 5 min after 5% isoflurane (ISO group) or 7% sevoflurane (SEV group) anesthesia. The blood melatonin concentrations during anesthesia in the ISO group increased significantly, from 65 +/- 60 to 170 +/- 90 pg x ml(-l); mean +/- SD ( P < 0.05), whereas those in the SEV group decreased, from 60 +/- 50 to 30 +/- 30 pg x ml(-l) ( P < 0.05). In conclusion, isoflurane increases, but sevoflurane decreases blood melatonin concentrations.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical TrialSafety and beneficial effect on body core temperature of a prewarmed plasma substitute--hydroxyethyl starch--during anesthesia.
We investigated, first, the safety of use and stability of a plasma substitute-hydroxyethyl starch (HES)-kept in a warming cabinet for a long period, and then the effect on body core temperature of the prewarmed HES in patients during urological surgery. ⋯ The use of HES products kept in a warming cabinet prior to surgery can maintain warm body temperature, easily, safely, and effectively.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical TrialAddition of epinephrine to intrathecal tetracaine augments depression of the bispectral index during intraoperative propofol sedation.
Epinephrine added to local anesthetic agents for spinal anesthesia is frequently used to prolong the duration of anesthesia. Epinephrine stimulates the alpha-adrenoceptor, and it is known that the alpha2-adrenoceptor agonists have a central inhibitory effect. We investigated the effect of intrathecal epinephrine during propofol sedation with spinal anesthesia, using a bispectral index (BIS) monitor. ⋯ Intrathecal epinephrine augments the sedative effect of propofol during spinal anesthesia.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Clinical TrialEffects of oral atenolol on volatile anesthetic induction with sevoflurane in adults.
To determine whether premedication with a beta-blocker can bring about a more rapid and smooth induction of anesthesia, we investigated the effect of oral premedication with atenolol on volatile anesthetic induction with sevoflurane by monitoring the cardiac output (CO) and bispectral (BIS) index. ⋯ Oral premedication with 25 mg of atenolol provides a more rapid decrease in BIS index and is recommended for use in stable volatile anesthetic induction with sevoflurane.
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Journal of anesthesia · Jan 2004
Randomized Controlled Trial Comparative Study Clinical TrialVolatile induction and maintenance of anesthesia using laryngeal mask airway in pediatric patients.