Journal of anesthesia
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Journal of anesthesia · Apr 2013
A pilot study of the pleth variability index as an indicator of volume-responsive hypotension in newborn infants during surgery.
The aim of this pilot study was to evaluate the diagnostic value of pleth variability index (PVI) to predict fluid responsiveness in newborn infants during surgery. ⋯ This preliminary evaluation shows that PVI may indicate VRH in newborn infants during surgery.
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Journal of anesthesia · Apr 2013
Increased carboxyhemoglobin level during liver resection with inflow occlusion.
Controlling stress responses associated with ischemic changes due to bleeding and ischemia/reperfusion injury is essential for anesthetic management. Endogenous carboxyhemoglobin (COHb) is produced in the oxidative degradation of heme proteins by the stress-response enzyme heme oxygenase. Although the COHb level is elevated in critically ill patients, changes in endogenous COHb during anesthesia have not been well investigated. ⋯ In addition, COHb changes were correlated with inflow occlusion time (P = 0.005, R(2) = 0.21). Neither total blood loss, transfusion volume of packed red blood cells, operation time, nor anesthetic time differed between patients with and without increased COHb. The results indicated that endogenous COHb levels were increased by inflow occlusion in patients undergoing liver resections, which suggests that changes in COHb may correlate with hepatic ischemia/reperfusion injury induced by inflow occlusion.