Journal of anesthesia
-
Journal of anesthesia · Jun 2013
Randomized Controlled TrialOral administration of aprepitant to prevent postoperative nausea in highly susceptible patients after gynecological laparoscopy.
The use of opioids following surgery is associated with a high incidence of postoperative nausea and vomiting (PONV). We conducted a prospective, randomized, double-blind, placebo-controlled study to investigate the effect of orally administered aprepitant, a neurokinin-1 receptor antagonist, for reducing PONV in patients with fentanyl-based, patient-controlled analgesia (PCA) given intravenously after gynecological laparoscopy. ⋯ Aprepitant 80 mg orally was effective in lowering the incidence of PONV in the first 48 h after anesthesia in patients receiving fentanyl-based PCA after gynecological laparoscopy.
-
Journal of anesthesia · Jun 2013
Randomized Controlled TrialA prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection.
Propofol injection is known to cause distressing pain, and various methods have been used to decrease this pain. We investigated the efficacy of the lidocaine + metoclopramide and lidocaine + ketamine combinations on modulating propofol injection pain. ⋯ The lidocaine-ketamine combination is most effective for decreasing the pain on propofol injection.
-
Journal of anesthesia · Jun 2013
Randomized Controlled TrialLevosimendan is superior to dobutamine as an inodilator in the treatment of pulmonary hypertension for children undergoing cardiac surgery.
To compare the effectiveness of levosimendan and dobutamine in reducing pulmonary artery pressure (PAP) and increasing cardiac output for children undergoing cardiac surgery. ⋯ Levosimendan is better than dobutamine for treatment of pulmonary hypertension of children undergoing cardiac surgery.