Journal of anesthesia
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Journal of anesthesia · Jan 2005
Randomized Controlled Trial Comparative Study Clinical TrialHemodynamic and catecholamine response to a rapid increase in isoflurane or sevoflurane concentration during a maintenance phase of anesthesia in humans.
The purpose of this study was to compare hemodynamic and catecholamine changes due to a sudden increase in inhalation anesthetic concentrations (isoflurane and sevoflurane) during surgery. ⋯ During surgery a sudden increase in isoflurane concentration induced larger changes in hemodynamics and sympathetic nerve activity than sevoflurane.
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Journal of anesthesia · Jan 2005
Randomized Controlled Trial Clinical TrialInsulin secretion and glucose utilization are impaired under general anesthesia with sevoflurane as well as isoflurane in a concentration-independent manner.
The dose-dependent effects of sevoflurane and isoflurane anesthesia on glucose tolerance were compared in humans. ⋯ Sevoflurane anesthesia impairs glucose tolerance to the same degree as does isoflurane anesthesia. Glucose intolerance during sevoflurane or isoflurane anesthesia is independent of agent and dosage up to 1.5 MAC.
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Journal of anesthesia · Jan 2005
Randomized Controlled Trial Clinical TrialEfficacy of landiolol in attenuating hemodynamic responses to local epinephrine infiltration in patients undergoing vaginal total hysterectomy.
Local epinephrine infiltration often causes beta1-adrenoceptor-mediated tachycardia, hypertension, and arrhythmia. Landiolol, a short acting beta1-adrenoceptor blocker, may represent the most ideal agent to attenuate these adverse effects. In this study, we examined the effects of landiolol on the hemodynamic changes resulting from local infiltration of epinephrine. ⋯ The present study suggests that landiolol 10 mg may be a more suitable dose than landiolol 5 mg to antagonize hyperdynamic states induced by local administration of epinephrine.
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Journal of anesthesia · Jan 2005
Informed consent for anesthesia: survey of current practices in Japan.
Anesthesia requires informed consent because it is an invasive procedure with certain risks. However, the state of informed consent for anesthesia in Japan remains unclear. The purpose of this survey was to examine the state of informed consent for anesthesia in Japan. ⋯ Although consent for anesthesia was obtained at more than 90% of departments, only 59.9% of departments would keep records of having obtained consent. This survey found that the explanation of anesthesia varied among hospitals and was not standardized in Japan. Further attention is needed on how to improve the documentation of informed consent.
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Journal of anesthesia · Jan 2005
Randomized Controlled TrialHow to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen.
Many studies have been conducted on how to decrease propofol injection pain, but none has been completely successful. In the present study, the most effective method was investigated by adding lidocaine or a nonsteroidal antiinflammatory drug or by changing the solvent. ⋯ Flurbiprofen 50 mg i.v. just before propofol injection completely abolished propofol injection pain. When it was administered 1 min before propofol injection it was less effective.