Der Schmerz
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Randomized Controlled Trial Comparative Study
[Comparison of the peripheral and central effects of opiates after iliac crest transplants. Reconstruction of severely atrophied maxilla].
Severe pain is one of the main problems after harvesting iliac crest transplants. In this randomized double-blind study differences in the peripheral and central effects of opiates for pain treatment in the iliac crest region after augmentation of the severely resorbed maxilla were examined. ⋯ The effect of centrally given opiates is more effective in the early postoperative period. In the early rehabilitation period the effect of intraoperatively local peripherally placed opiates is superior to intraoperatively centrally administered opiates.
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Randomized Controlled Trial Comparative Study
[Pain therapy using stimulating catheters after total knee arthroplasty].
Epidural analgesia and continuous femoral nerve blocks are often used for pain therapy after total knee arthroplasty. The additional use of a continuous sciatic nerve block is controversially discussed. To avoid the problem of inaccurate placement a stimulating catheter may be useful. The aim of this study was to compare the effectiveness of a continuous femoral nerve block with an additional continuous sciatic nerve block for improved functional recovery and pain relief. ⋯ Using stimulating catheters for pain therapy the three methods are largely comparable and other parameters should be used for individual selection.
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Randomized Controlled Trial Comparative Study
[Desire for early retirement and therapy of chronic back pain: relevance of social medical variables for outpatient psychotherapeutic treatment].
This study investigated the influence of patients' desire for early retirement on the success of an outpatient cognitive behavioural treatment (CBT) in patients with chronic back pain. Previous studies have shown that the desire for early retirement and social compensation had a negative influence on therapy outcome, e.g. pain intensity and pain disability. This study was conducted to reassess whether these results can be replicated in an outpatient CBT setting. ⋯ CBT in an outpatient setting seems to be an effective treatment for patients with chronic back pain and even patients with a desire for early retirement benefit from treatment.
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Randomized Controlled Trial
[Modulation of cortical pain processing by cyclooxygenase inhibition: a functional MRI study].
Little is known about changes in brain activity with pharmacological modulation of hyperalgesia. Therefore, we sought to investigate the cerebral processing of hyperalgesia and acute pain using functional magnetic resonance imaging (fMRI) and pharmacological modulation with cyclooxygenase (COX) inhibitors. ⋯ This study provides new evidence for the involvement of COX inhibitors in modulating the cerebral activity associated with acute pain and hyperalgesia. Our results hint at a differential modulation of brain areas under either analgesia or antihyperalgesia.
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Randomized Controlled Trial
[Electrical point stimulation (P-STIM) via ear acupuncture: a randomized, double-blind, controlled pilot study in patients undergoing laparoscopic nephrctomyX].
The aim of this study was to determine whether P-STIM-verum in patients undergoing laparoscopic nephrectomies resulted in a lower consumption of analgesics and an improvement of pain scores compared with P-STIM-placebo when administered for acute peri- and postperative pain. ⋯ In this study we were able to demonstrate, that pre- and postoperative P-STIM applied in patients undergoing laparoscopic nephrectomies seems to be an effective, simply applied method with few side-effects for reducing pain and postoperative analgesic consumption.