Annals of medicine
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We systematically reviewed neuroimaging predictors for malignant brain oedema (MBE) after thrombectomy in patients with ischemic stroke. ⋯ Lower ASPECTS and longer arterial occlusion at baseline, and post-thrombectomy CT contrast enhancement increased risk of MBE. Reperfusion after thrombectomy, more reserved brain volume and good collaterals at baseline and post-thrombectomy reduced its risk.
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Meta Analysis Comparative Study
Endovascular therapy versus best medical care for acute ischemic stroke with distal medium vessel occlusion: a systematic review and meta-analysis.
With the refinement of catheter technology, distal medium vessel occlusions (DMVOs) are now viewed as amenable to endovascular treatment (EVT) but its efficacy and safety remains unclear in AIS patients with DMVO. ⋯ For patients with AIS and DMVO occlusion, EVT fails to improve functional prognosis while increasing sICH incidence. More randomized controlled trials are needed in the future to confirm these results.
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This systematic review and meta-analysis aimed to evaluate differences in cardiopulmonary fitness between healthy controls and children/adolescents with chronic kidney disease (CKD) and the effects of exercise training. ⋯ This systematic review and meta-analysis of observational studies and clinical trials that included children/adolescents with CKD found that cardiorespiratory fitness is severely reduced in this population and that exercise training may be an effective strategy for improvement. Given the low evidence certainty, additional high-quality trials are necessary.
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Meta Analysis
Prognostic and clinicopathological value of C-reactive protein in patients with bladder cancer: a meta-analysis.
The prognostic value of C-reactive protein (CRP) in patients with bladder cancer (BCa) has been widely analysed; however, the results remain conflicting. Therefore, we performed this meta-analysis to identify the precise role of CRP level in predicting BCa prognosis. ⋯ Elevated CRP levels were significantly related to poor OS, CSS, RFS and PFS of BCa patients with BCa. CRP could act as a reliable biomarker for predicting the short- and long-term survival of patients with BCa in clinical practice.
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Meta Analysis
Sleep features and the risk of type 2 diabetes mellitus: a systematic review and meta-analysis.
This study aimed to assess the associations between multidimensional sleep features and type 2 diabetes mellitus (T2DM). ⋯ A U-shaped relationship was observed between sleep duration and type 2 diabetes mellitus (T2DM), with the lowest risk occurring at a sleep duration of 7 to 8 h. Additionally, poor sleep quality, evening chronotypes, and daytime napping exceeding 30 min emerged as potential risk factors for T2DM. These high-risk sleep characteristics interacted with one another, amplifying the overall risk of developing the disease.