Respiratory medicine
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Respiratory medicine · Feb 2009
Randomized Controlled TrialImpact of volume targeting on efficacy of bi-level non-invasive ventilation and sleep in obesity-hypoventilation.
Volume targeting by bi-level positive pressure ventilation (BPPV) has recently been made available by several manufacturers for home care ventilators. Although it may improve nocturnal ventilation, we hypothesized that increased pressure swings related to volume targeting may have a deleterious effect on sleep structure and patient comfort. ⋯ In stable patients treated by BPPV for obesity-hypoventilation, volume targeting improved control of nocturnal hypoventilation at the expense of a slight decrease in objective and subjective sleep quality, and comfort of ventilation.
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Respiratory medicine · Feb 2009
Randomized Controlled TrialModulation of operational lung volumes with the use of salbutamol in COPD patients accomplishing upper limbs exercise tests.
Pulmonary dynamic hyperinflation (DH) is an important factor limiting the physical capacity of patients with COPD. Inhaled bronchodilator should be able to reduce DH. ⋯ We conclude that the use of bronchodilator increases the IC of patient with COPD and may help not to increase the DH during a maximal exercise with the arms.