Respiratory medicine
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Respiratory medicine · Jul 2010
Randomized Controlled Trial Multicenter StudyCombining tiotropium and salmeterol in COPD: Effects on airflow obstruction and symptoms.
Clinical information on 24-h spirometric efficacy of combining tiotropium and salmeterol compared to single-agent therapy is lacking in patients with COPD. ⋯ Compared to single-agent therapy, combination therapy of tiotropium plus salmeterol in COPD provided clinically meaningful improvements in airflow obstruction and dyspnea as well as a reduction in reliever medication.