Urology
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Randomized Controlled Trial Comparative Study Clinical Trial
Antibiotic prophylaxis for patients undergoing transurethral resection of the prostate.
To evaluate the prevention of urinary tract infections (UTIs) after transurethral resection of the prostate (TURP) in a prospective randomized study using a quinolone antibiotic (fleroxacin) to compare the efficacy of: (1) a single oral dose, (2) a single intravenous (IV) dose, and (3) an extended regimen consisting of an initial IV dose followed by oral therapy until removal of the urinary catheter, but for less than 6 days. ⋯ A single oral dose of a fluoroquinolone agent provided optimum prophylaxis for patients undergoing TURP.