Journal of neurosurgical anesthesiology
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J Neurosurg Anesthesiol · Jan 2016
Traumatic Brain Injury Patients With a Glasgow Coma Scale Score of ≤8, Cerebral Edema, and/or a Basal Skull Fracture are More Susceptible to Developing Hyponatremia.
Traumatic brain injury (TBI) is a common injury treated at the neurosurgery department. The incidence rate is approximately 3% in the general population and the mortality rate is 25%. The incidence of hyponatremia following TBI is 33%. Hyponatremia is one of the main causes of disability and/or death in TBI patients. This study investigated the epidemiology of hyponatremia following TBI. ⋯ TBI patients with a GCS score ≤8, cerebral edema, and/or a basal skull fracture are particularly prone to developing hyponatremia. These patients require additional treatment that should entail the normalization of serum sodium levels to prevent deterioration of their condition.
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J Neurosurg Anesthesiol · Jan 2016
Randomized Controlled TrialThe Opioid-sparing Effect of Intraoperative Dexmedetomidine Infusion After Craniotomy.
We conducted a randomized trial to evaluate the opioid-sparing effect of an intraoperative infusion of dexmedetomidine (DEX) after craniotomy. ⋯ An intraoperative infusion of DEX reduced cumulative morphine consumption and adverse effects after craniotomy.
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J Neurosurg Anesthesiol · Jan 2016
Randomized Controlled TrialLidocaine Did Not Reduce Neuropsychological-Cognitive Decline in Patients 6 Months After Supratentorial Tumor Surgery: A Randomized, Controlled Trial.
: There is equivocal evidence examining cognitive improvement in response to lidocaine during cardiac surgery; however, no study has examined its effect on postoperative neuropsychological-cognitive decline after supratentorial tumor surgery. ⋯ Intraoperative infusion of lidocaine does not significantly decrease the incidence of postoperative neuropsychological-cognitive decline in patients 6 months after supratentorial tumor surgery.
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J Neurosurg Anesthesiol · Jan 2016
Randomized Controlled Trial Comparative StudyComparison of the Effects of 3 Methods of Intrathecal Bupivacaine, Bupivacaine-Fentanyl, and Bupivacaine-Fentanyl-Magnesium Sulfate on Sensory Motor Blocks and Postoperative Pain in Patients Undergoing Lumbar Disk Herniation Surgery.
The aim of this study was to investigate the effects of adding intrathecal (IT) fentanyl and magnesium sulfate (MgSO4) to bupivacaine on sensory motor blocks and postoperative pain in patients undergoing lumbar disk herniation surgery. ⋯ In patients undergoing lumbar disk herniation surgery, IT MgSO4 in combination with bupivacaine-fentanyl can decrease severity of postoperative pain and analgesic consumption without additional side effect.