Journal of Ayub Medical College, Abbottabad : JAMC
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J Ayub Med Coll Abbottabad · Jul 2012
Randomized Controlled TrialOral clonidine for attenuation of haemodynamic response to laryngoscopy and endotracheal intubation in known hypertensive patients.
Sympathetic response associated with laryngoscopy and endotracheal intubation is recognised as a potential cause for a number of complications especially in hypertensive patients. Various methods have been used to attenuate these haemodynamic responses; however most of the studies are in normotensive patients. The aim of our study was to compare the effect of oral clonidine and 1/V fentanyl with oral placebo and I/V fentanyl in attenuating the haemodynamic responses to laryngoscopy and intubation in known hypertensive patients. ⋯ Clonidine, under the present study design attenuates the haemodynamic response to laryngoscopy and endotracheal intubation in known hypertensive patients.