Burns : journal of the International Society for Burn Injuries
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Contracture deformities affecting the flexor aspect of the elbow joint and the 1st web space are not uncommon sequelae of burns. Surgical treatment is contemplated in those patients with established contractural deformities in whom non-surgical treatment is ineffective or functional integrity of the joint is at jeopardy. Surgical treatment consists of incising the scar tissue to release joint contracture and covering the defect that might result with skin grafting or various tissue flaps. In this work, we used a modification of the multilobed propeller flap to treat eight patients with contracture deformities. ⋯ The new modification has the advantages of being flexible, can be tailored to best match the defect so that it can be closed primarily or needs smaller skin grafts, can be used even when there is much scarring and, finally, the resultant appearance is cosmetically acceptable with little donor morbidity, if any.
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Burns are one of the most significant health problems throughout the world, leading to prolonged hospitalisation and hence increased expense for the patients, their families and society. Today, the prognosis of patients with burns is dependent, apart from adequate treatment, upon the health-care system and health-care professionals, regarding not only survival, but also lifelong quality of life. This study aims to assess quality of life of adult patients with severe burns. ⋯ The quality of life for people who have sustained a burns should be recognised and valued by the burn team in all phases of burn care.
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To determine the incidence, magnitude of injury, fluid management, role of surgery and outcome in newborns and infants under 4 months of age admitted to a Burns Unit. ⋯ Neonates and infants are very vulnerable and preventable environmental factors are often implicated. Fire and hot water are the most common causes resulting in significant physical trauma. Resuscitation especially during the first few days of life can be problematic. Wound infection and sepsis are common and surgery should be individualised. Long-term outcome is very satisfactory for those with small burns however those with larger burns may remain permanently disfigured.
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This study was planned to design a mouse model for studying sulphur mustard (SM)-induced skin injury. SM was applied dermally at dose of 5 or 10 mg kg(-1) in polyethyleneglycol-300 (PEG-300) or dimethylsulphoxide (DMSO) or acetone once. The changes in body weight, organ body weight indices (OBWI) and haematological and oxidative stress parameters were investigated over a period of 3-7 days and supported by histopathological observations. ⋯ These biochemical changes were supported by the histological observations, which revealed pronounced toxic effect and damage to liver, kidney and spleen after dermal application of SM diluted in PEG-300 or DMSO. The skin showed similar microscopic changes after dermal application of SM in all the three diluents, however; the severity of lesions was found to be time and dose dependent. It can be concluded that dermal exposure of SM diluted in acetone can be used to mimic SM-induced skin toxicity without systemic toxicity in a mouse model.