Critical reviews in oncology/hematology
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Crit. Rev. Oncol. Hematol. · Oct 2018
ReviewRole of vena cava filters for the management of cancer-related venous thromboembolism: Systematic review and meta-analysis.
Results from cohort studies evaluating the benefit in prevention of recurrent Venous Thromboembolism in cancer population are heterogeneous and controversial. ⋯ Vena cava filter did not show benefits for recurrent venous thromboembolism prevention in the cancer-patients population.
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Crit. Rev. Oncol. Hematol. · Oct 2018
ReviewBiomarkers of response to immune checkpoint blockade in cancer treatment.
Immune checkpoint inhibitors (ICPis) are emerging as the new corner stone of cancer treatment due to their ability to produce durable responses in patients with various cancers. But, objective responses to ICPis vary among each type of cancer. ⋯ However, given the complexity of the tumor microenvironment and the dynamic interaction between tumor and immune cells, development of robust biomarkers to predict patients who are likely to respond to treatment with ICPis remains a challenge. In this review we present an overview of the immune monitoring strategies that are currently in use to enable appropriate patient selection.