The Journal of dermatological treatment
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Randomized Controlled Trial
The efficacy of combined PUVA and low-dose azathioprine for early and enhanced repigmentation in vitiligo patients.
Immunosuppressive agents are used widely in the treatment of vitiligo. Corticosteroids are used either alone or as adjuvant therapy by many practitioners. Cyclophosphamide and cycloporine-A have also been used with variable success. Azathioprine may have the potential for the treatment of vitiligo alone or in combination with other modalities. ⋯ Azathioprine may potentiate the repigmentary effects of PUVA therapy in vitiligo patients. A limitation of the study is the lack of validated measures for vitiligo assessment.