The British journal of dermatology
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Case Reports Comparative Study Clinical Trial Controlled Clinical Trial
Fresh versus cryopreserved cultured allografts for the treatment of chronic skin ulcers.
Both fresh and cryopreserved cultured epithelial allografts were used to treat 20 patients with a total of 30 chronic ulcers. A profound stimulation of host epithelialization from the wound edges and epidermal appendages was observed. Our data suggest that allografts, prepared using a simple cryopreservation technique, retain their morphological and functional characteristics, and are as effective as fresh allografts in healing chronic ulceration.