The British journal of dermatology

The most recent articles from: Br. J. Dermatol. January 2006

Br. J. Dermatol. · Jan 2006

Randomized Controlled Trial

Randomized, double-blind, placebo-controlled prospective study of the efficacy of topical anaesthesia with a eutetic mixture of lignocaine 2.5% and prilocaine 2.5% for topical 5-aminolaevulinic acid-photodynamic therapy for extensive scalp actinic keratoses.

Photodynamic therapy (PDT) is an effective treatment modality for the treatment of extensive scalp actinic keratoses (AKs), but pain is a significant drawback when treating large areas with topical PDT using 5-aminolaevulinic acid (ALA) as sensitizer. A recent study has shown that use of tetracaine gel (Ametop) did not significantly reduce pain associated with PDT. ⋯ Our data do not support the routine use of topical anaesthesia with Emla for topical PDT.

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