European journal of internal medicine
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Eur. J. Intern. Med. · Jul 2022
Meta AnalysisInterleukin-6 inhibitors reduce mortality in coronavirus disease-2019: An individual patient data meta-analysis from randomized controlled trials.
To assess the efficacy of IL-6 inhibitors compared to standard of care (SOC) in COVID-19 patients. ⋯ This meta-analysis of individual patient data from randomized trials shows that IL-6 inhibitors significantly reduce the risk of death compared to SOC. IL-6 inhibitors are also associated with better outcomes in terms of intubation and discharge rates compared to SOC.