European journal of internal medicine
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Eur. J. Intern. Med. · Jan 2025
Risk trajectory of cardiovascular events after an exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis.
Exacerbations of chronic obstructive pulmonary disease (COPD) are known to increase the risk of cardiovascular (CV) events and mortality. However, the temporal trend of this risk has not fully elucidated. This systematic review and meta-analysis aims to quantify the risk of CV events after COPD exacerbations over different time periods. ⋯ COPD exacerbations significantly increase the risk of acute CV events, particularly within the first 30 days. Optimal strategies to reduce cardiopulmonary risk are needed.
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Eur. J. Intern. Med. · Jan 2025
Opt-In versus opt-out for the secondary use of routinely recorded health data: A randomized controlled trial.
Optimal data availability for secondary use is crucial for continuous improvement in healthcare. At the same time, it is imperative to uphold patients' rights to be informed, to control the use of their health data and to protect their privacy. To balance these two needs, we investigated which consent procedure (opt-in or opt-out) would be most supportive of data availability. ⋯ An opt-out procedure appears to be more effective in ensuring optimal data availability with less bias for the secondary use of health data compared to opt-in. To uphold patient control over data, it is pivotal that patients are well-informed about the consent procedure.