European journal of internal medicine
-
Eur. J. Intern. Med. · Feb 2020
Randomized Controlled TrialRivaroxaban for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer. Design of the PRO-LAPS II STUDY.
The clinical benefit of extending prophylaxis for venous thromboembolism (VTE) beyond hospital discharge after laparoscopic surgery for cancer is undefined. Extended prophylaxis with rivaroxaban is effective in reducing post-operative VTE after major orthopedic surgery without safety concern. ⋯ The PROLAPS II is the first study with an oral anti-Xa agent in cancer surgery. The study has the potential to improve clinical practice by answering the question on the clinical benefit of extending prophylaxis after laparoscopic surgery for colorectal cancer.
-
Eur. J. Intern. Med. · Jan 2020
Randomized Controlled TrialTreating periodontal disease in patients with myocardial infarction: A randomized clinical trial.
Periodontitis has been associated with coronary artery disease, but the impact of a periodontal treatment on the endothelial function of patients with a recent ST-segment elevation myocardial infarction (STEMI) was not investigated. ⋯ NCT02543502 (https://clinicaltrials.gov/ct2/show/NCT02543502?term=NCT02543502&rank=1).
-
Eur. J. Intern. Med. · Nov 2019
Randomized Controlled TrialEvaluation of a technology assisted physical activity intervention among hospitalised patients: A randomised study.
Physical inactivity is common during hospitalisation and poses a threat to functional capacity and independency in the elderly. ⋯ A simple technology assisted physical activity intervention with visual feedback to encourage mobility was not effective at increasing time spent out of bed among hospitalised patients. With feedback, a subgroup of patients with independent walking abilities increased time out of bed and may benefit from this type of intervention.
-
Eur. J. Intern. Med. · Sep 2019
Randomized Controlled Trial Multicenter StudyHereditary angioedema, emergency management of attacks by a call center.
Hereditary angiœdema (HAE) is a rare autosomal dominant disease characterized by recurrent, unpredictable, potentially life-threatening swelling. Objective is to assess the management of the acute HAE attacks in the real life setting through a call center in France. ⋯ Use of emergency departments and hospitalizations are reduced by the use of a coordinated national call center in HAE after therapeutic education program that promoted self-administration of specific treatment and use of call to call center.
-
Eur. J. Intern. Med. · May 2016
Randomized Controlled Trial Multicenter Study Observational StudyPrior thromboprophylaxis and outcome in patients experiencing acute venous thromboembolism after an acute medical illness.
Even despite the use of thromboprophylaxis, some patients with an acute medical illness develop symptomatic venous thromboembolism (VTE). It is unclear whether the outcome in these patients is different in those in whom prophylaxis was not prescribed. ⋯ The outcome in patients with VTE provoked by medical immobilization was not influenced by the use of thromboprophylaxis during the period of immobility.