The British journal of general practice : the journal of the Royal College of General Practitioners
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Meta Analysis
Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds.
Centor and McIsaac scores are both used to diagnose group A beta-haemolytic streptococcus (GABHS) infection, but have not been compared through meta-analysis. ⋯ Both Centor and McIsaac scores provide only fair discrimination of those with and without GABHS, and appear broadly equivalent in performance. The poor calibration for a positive test result suggests other point-of-care tests are required to rule in GABHS; however, with both Centor and McIsaac scores, a score of ≤0 may be sufficient to rule out infection.