Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 2022
ReviewVasoactive and/or inotropic drugs in initial resuscitation of burn injuries: A systematic review.
According to current guidelines initial burn resuscitation should be performed with fluids alone. The aims of the study were to review the frequency of use of vasoactive and/or inotropic drugs in initial burn resuscitation, and assess benefits and harms of adding such drugs to fluids. ⋯ This systematic review revealed that there is lack of evidence regarding benefits and harms of using vasoactive and/or inotropic drugs in addition to fluids during early resuscitation of patients with major burns.
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Acta Anaesthesiol Scand · May 2022
The use of melatonin in Danish intensive care departments - a nationwide observational study.
Melatonin is widely employed as a hypnotic in various patient groups. In intensive care patients, melatonin seems to be increasingly used due to potential clinical effects and a favorable safety profile. ⋯ Melatonin is widely and increasingly used in Danish intensive care departments. The more than doubled usage of melatonin in the study period advocate for further studies employing validated outcomes of sleep and other patient-relevant outcomes.
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Acta Anaesthesiol Scand · May 2022
Regional anaesthesia in patients on antithrombotic drugs - a joint ESAIC/ESRA guideline: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.
The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Regional anaesthesia in patients on antithrombotic drugs - a joint ESAIC/ESRA guideline. This clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists providing regional anaesthesia to adult patients on antithrombotic drugs.
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Acta Anaesthesiol Scand · May 2022
Agents intervening against delirium in the intensive care unit (AID-ICU) trial-protocol for a secondary Bayesian analysis.
Delirium is highly prevalent in the intensive care unit (ICU) and associated with high morbidity and mortality. The antipsychotic haloperidol is the most frequently used agent to treat delirium although this is not supported by solid evidence. The AID-ICU trial investigates the effects of haloperidol versus placebo for the treatment of delirium in adult ICU patients. ⋯ The results of this secondary, pre-planned Bayesian analysis will complement the primary frequentist analysis of the AID-ICU trial and facilitate a nuanced and probabilistic interpretation of the trial results. This article is protected by copyright. All rights reserved.