Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 2001
Randomized Controlled Trial Clinical TrialOnset and duration of action of rocuronium--from tracheal intubation, through intense block to complete recovery.
The primary objective of this study was to establish the relation between the post tetanic count (PTC) and the time to reappearance of the first response (T1) in train-of-four (TOF) nerve stimulation following rocuronium 0.6 mg/kg, 0.9 mg/kg, and 1.2 mg/kg. The secondary objective was to evaluate the intubation conditions after 1 min. ⋯ The PTC method can be used to predict the time to first response to TOF nerve stimulation during intense rocuronium induced neuromuscular blockade. The relation between PTC and the time to T1 was prolonged after 1.2 mg/kg compared with 0.6 mg/kg and 0.9 mg/kg. No further improvement in intubation conditions at 60 s was evident by increasing the rocuronium dose from 0.9 mg/kg to 1.2 mg/kg.
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Acta Anaesthesiol Scand · May 2001
Randomized Controlled Trial Clinical TrialEffect of preincisional ilioinguinal and iliohypogastric nerve block on postoperative analgesic requirement in day-surgery patients undergoing herniorrhaphy under spinal anaesthesia.
By choosing spinal anaesthesia instead of general anaesthesia, and by infiltrating the wound area with local anaesthetic the need for postoperative analgesics may be reduced. An ilioinguinal and iliohypogastric nerve block (IINB) in inguinal herniorrhaphy was, therefore, studied in a day surgery setting in combination with a spinal block. ⋯ It is concluded that no long-term analgesia could be demonstrated by a preincisional IINB performed during spinal anaesthesia in day-surgery inguinal herniorrhaphy patients. Thus, reduced analgesic requirement was seen only for about 6 h postoperatively.
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Acta Anaesthesiol Scand · May 2001
Comparative Study Clinical TrialDoes discontinuation of desflurane at the time of neostigmine administration speed recovery from cisatracurium block compared to that with a propofol-based technique?
Volatile anaesthetics are known to influence the effect of neostigmine as an antagonist of neuromuscular block. The aim of the present study was to investigate whether discontinuation of desflurane at the time of neostigmine administration shortens reversal time from cisatracurium block, compared to that with a propofol-based anaesthesia. ⋯ Discontinuing desflurane does not speed neostigmine-induced recovery from cisatracurium neuromuscular block, when compared to that during propofol-based anaesthesia.
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Although drug administration through an intrathecal catheter is widely used in the study of spinal pharmacology, the catheter positions in transverse plane that may cause a limited spread of a solution remain unclear. In the first step to clarify this issue, the distribution of the intrathecal catheter position was investigated in rats. ⋯ Chronic intrathecal catheters were variously located in the rat spinal subarachnoid space in the transverse plane, and lateral subarachnoid placement of the catheter (58%) was frequently observed, whereas dorsal subarachnoid placement occurred in 33%.
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Acta Anaesthesiol Scand · May 2001
Randomized Controlled Trial Comparative Study Clinical TrialEase of laryngeal passage during fibreoptic intubation: a comparison of three endotracheal tubes.
The use of a fibreoptic bronchoscope to facilitate endotracheal intubation is well established in modern anaesthetic practice. Difficulty may be encountered when inserting an endotracheal tube over the fibrescope as the bevelled tip can impinge on the vocal cords or epiglottis and impede advancement through the laryngeal inlet. Intavent have recently developed a tapered tip tube for use with their Intubating Laryngeal Mask Airway. A randomised, double-blind study was performed to compare the ease of railroading three different tubes over a fibrescope placed in the trachea. ⋯ The Intavent tube was found to be superior for nasotracheal fibreoptic intubation to either the Mallinckrodt reinforced tube (P<0.034) or the Portex Blue Line tube (P<0.004).