Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2003
Randomized Controlled Trial Comparative Study Clinical TrialInfluence of total intravenous and inhalational anaesthesia on haemostasis during tympanoplasty.
Surgical trauma leads to systemic changes in haemostasis. Haematological changes activated by surgery may become so prominent that changes caused by anaesthesia might be hidden or underestimated. Therefore, we have undertaken a prospective study to compare the behaviour of selected factors involved in the coagulation and fibrinolytic systems. ⋯ Presuming a minimal traumatic effect of surgical procedure on the determined variables, we conclude that different anaesthetic techniques have a negligible effect on platelet activation and fibrinolysis. The clinical relevance of coagulation activation and fibrinolysis during different anaesthetic techniques remains to be investigated.
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Acta Anaesthesiol Scand · Nov 2003
Prevalence and predictive value of ionized hypocalcemia among critically ill patients.
Ionized hypocalcemia is common among critically ill patients, and it has been shown to correlate with increased mortality. The purpose of this study was to examine the performance and independence of ionized calcium (Ca2+) in prediction of all-cause day-30 mortality among critically ill adult patients. ⋯ Ionized hypocalcemia is common among critically ill adults and it is associated with increased mortality. Although non-survivors and survivors differ significantly in admission Ca2+, hypocalcemia is not independently associated with day-30 mortality.
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Acta Anaesthesiol Scand · Nov 2003
Biography Historical ArticleThe first intensive care unit in the world: Copenhagen 1953.
After an extensive survey of the medical literature we present compelling evidence that the first intensive care unit was established at Kommunehospitalet in Copenhagen in December 1953. The pioneer was the Danish anaesthetist Bjørn Ibsen. The many factors that interacted favourably in Copenhagen to promote the idea of intensive care therapy, half a century ago, are also described.