Acta anaesthesiologica Scandinavica
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Ephedrine is one of the most commonly used non-catecholamine sympathomimetic agents. It is used in operating rooms and critical care settings worldwide. While it has many side effects, its ability to rapidly raise blood pressure makes it an ideal agent to maintain homeostasis as well as in emergency situations. While its effects are known to be mediated by an alpha-mediated mechanism, the exact alpha subtype is unknown. In addition, no studies using ephedrine have been performed in the pulmonary vascular bed of the cat. ⋯ Ephedrine has significant vasopressor activity in the pulmonary vascular bed of the cat meditated predominantly by alpha1 adrenergic receptor activation.
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Acta Anaesthesiol Scand · Sep 2003
Randomized Controlled Trial Clinical TrialPatient-controlled regional analgesia (PCRA) with ropivacaine after arthroscopic subacromial decompression.
The aim of the study was to evaluate postoperative analgesia and safety of wound instillation of ropivacaine either by a single dose or a patient-controlled regional anaesthesia (PCRA) technique. ⋯ Preoperative intrabursal prilocaine with epinephrine + postoperative subacromial administration of ropivacaine by PCRA-technique provided the most effective analgesia with no major side-effects. The free plasma concentrations of ropivacaine were far below toxic concentrations.
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Acta Anaesthesiol Scand · Sep 2003
Randomized Controlled Trial Clinical TrialIntravenous clonidine prolongs bupivacaine spinal anesthesia.
Prolongation of spinal anesthesia by oral clonidine premedication has been known. We hypothesized that intravenous clonidine administered after the spinal block may prolong spinal anesthesia. ⋯ Intravenous clonidine administration within 1 h after the spinal block prolonged bupivacaine spinal anesthesia for approximately 1 h without adverse effects.
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Acta Anaesthesiol Scand · Sep 2003
ReviewSevoflurane: an ideal agent for adult day-case anesthesia?
Sevoflurane has several properties which make it potentially useful as a day case anaesthetic. Following induction of anaesthesia with propofol, awakening from sevoflurane is faster compared to isoflurane, faster or similar compared to propofol and comparable (in the majority of studies) to desflurane. ⋯ When used as a maintenance anaesthetic, the incidence of postoperative nausea and vomiting after sevoflurane is comparable to other inhaled anaesthetics, but this complication appears more common after inhaled inductions. The tolerability and low solubility of sevoflurane facilitate titration of anaesthesia and may reduce the need for opioid analgesia, which in turn may limit the occurrence of nausea and vomiting.
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Acta Anaesthesiol Scand · Sep 2003
Comparative StudyThe psychometric properties of Chinese pain intensity verbal rating scale.
This study investigates the validity and reliability of the Chinese pain intensity verbal rating scale (C-PIVRS). ⋯ The two pain scales have a comparable level of reliability and validity for assessing pain intensity in Chinese adults.