Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2009
Case ReportsExtremely prolonged neuromuscular blockade after rocuronium: a case report.
It is known that the duration of rocuronium action can be prolonged in elderly patients and that such action shows important interindividual variability. We report a case of prolonged neuromuscular block lasting 11 h, in a woman subjected to kidney transplantation. The possible causes of such prolonged action, inherent to the drug, or related to external factors, are commented.
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Acta Anaesthesiol Scand · Aug 2009
Anti-ischemic effects of inotropic agents in experimental right ventricular infarction.
Right ventricular (RV) function is an important determinant of survival after myocardial infarction. The efficacy of reperfusion therapy might be increased by the cardioprotective action of inotropic agents, which are used for symptomatic therapy in situations with compromised hemodynamics. Therefore, we used a porcine model of RV ischemia and reperfusion (IR) injury to study the influence of milrinone, levosimendan and dobutamine on the extent and degree of myocardial injury. ⋯ Cardioprotective properties of milrinone and levosimendan were demonstrated for the first time in a clinically relevant model of RV infarction.
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Acta Anaesthesiol Scand · Aug 2009
Case ReportsAwake tracheal intubation using the Airtraq laryngoscope: a case series.
The Airtraq laryngoscope (AL) is a new single use indirect laryngoscope designed to facilitate tracheal intubation in anaesthetised patients either with normal or difficult airway anatomy. It is designed to provide a view of the glottis without alignment of the oral, pharyngeal and tracheal axes. ⋯ An awake intubation under sedation and topical airway anaesthesia was chosen. We consider that the AL can be used effectively to accomplish an awake intubation in patients with a suspected or known difficult airway and may be a useful alternative where other methods for awake intubation have failed or are not available.
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Acta Anaesthesiol Scand · Aug 2009
Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest.
Therapeutic hypothermia (TH) after cardiac arrest protects from neurological sequels and death and is recommended in guidelines. The Hypothermia Registry was founded to the monitor outcome, performance and complications of TH. ⋯ Half of the patients survived, with >90% having a good neurological function at long-term follow-up. Factors related to the timing of TH had no apparent association to outcome. The incidence of adverse events was acceptable but the risk of bleeding was increased if angiography/PCI was performed.
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Acta Anaesthesiol Scand · Aug 2009
Prospective evaluation of the time to peak effect of propofol to target the effect site in children.
The plasma-effect site equilibration rate constant (k(e0)) of propofol has been determined in children with the use of the time to maximum effect (t(peak)), however, it has not been validated. The objective was to measure the t(peak;) of propofol with two depths of anesthesia monitors in children and to evaluate these measurements with a target-controlled infusion (TCI) system. ⋯ The small delay between the evolution of Ce of propofol and the observed effect suggests that this can be a useful model to target the effect site in children.