Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2013
Case ReportsLaryngeal spasm after general anaesthesia due to Ascaris lumbricoides.
Postoperative upper airway obstruction during recovery from general anaesthesia may have several causes. This is a report of a young girl who developed laryngeal spasm as a result of an ectopic roundworm Ascaris lumbricoides.
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Acta Anaesthesiol Scand · Aug 2013
Comparative StudySevoflurane alters the expression of receptors and enzymes involved in Aβ clearance in rats.
Patients with Alzheimer's disease (AD) exhibit a failure in the clearance of amyloid β peptides (Aβ) from the central nervous system. Previous studies have suggested an association between anesthesia and the occurrence of AD. The aim of the present report was to further explore this possibility. ⋯ Sevoflurane leads to a reduction in the levels of LRP-1, while increasing RAGE and decreasing IDE and NEP in both aged and, to a lesser extent, young rat's brain. These receptor and enzymatic changes may promote the accumulation of Aβ in brain tissues and thus exacerbate Alzheimer's-like pathology.