Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2018
Effects of combined helium pre/post-conditioning on the brain and heart in a rat resuscitation model.
The noble gas helium induces cardio- and neuroprotection by pre- and post-conditioning. We investigated the effects of helium pre- and post-conditioning on the brain and heart in a rat resuscitation model. ⋯ Treatment with helium reduced apoptosis in our resuscitation model. Differential expression levels of Caveolin-1, Caveolin-3 and Hexokinase II in the heart were found after helium pre- and post-conditioning. No beneficial effects were seen on neurofunctional outcome.
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Acta Anaesthesiol Scand · Jan 2018
Editorial CommentBiomarkers of acute kidney injury - a mission impossible?
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Acta Anaesthesiol Scand · Jan 2018
Randomized Controlled Trial Comparative StudyA randomized trial of automated intermittent ropivacaine administration vs. continuous infusion in an interscalene catheter.
Ultrasound-guided interscalene nerve block with ropivacaine as local anesthetic agent given as boluses or continuous infusion is the preferred pain management after major shoulder surgery. The use of automated intermittent boluses has been shown to be superior to continuous infusion in sciatic and epidural nerve block. ⋯ Automated intermittent boluses did not reduce pain or rescue opioid consumption compared with continuous infusion of ropivacaine. The automated intermittent bolus group had significantly less force on coughing and more hoarseness.
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Acta Anaesthesiol Scand · Jan 2018
Outcomes after cancelled helicopter emergency medical service missions due to concurrencies: a retrospective cohort study.
Appropriate dispatch criteria and helicopter emergency medical service (HEMS) crew decisions are crucial for avoiding over-triage and reducing the number of concurrencies. The aim of the present study was to compare patient outcomes after completed HEMS missions and missions cancelled by the HEMS due to concurrencies. ⋯ Patients in the HEMS group seemed to be critically ill more often and received more emergency interventions, but the two groups had similar in-hospital mortality. Patients with pre-hospital signs of acute threat to life were younger and presented increased survival in the HEMS group.