Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Oct 2019
Delayed cerebral ischaemia in patients with aneurysmal subarachnoid haemorrhage: Functional outcome and long-term mortality.
Delayed cerebral ischaemia (DCI) is one of the most frequent complications of aneurysmal subarachnoid haemorrhage (aSAH). The purpose of the present retrospective cohort study of patients with aSAH was to identify the association between DCI, functional outcome and 4-year mortality. ⋯ DCI may be associated with both short- and long-term morbidity and mortality in patients with aSAH.
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Acta Anaesthesiol Scand · Oct 2019
Observational StudyInadequate emergence after non-cardiac surgery-A prospective observational study in 1000 patients.
The post-anaesthetic phase is most often uncomplicated, but patients may experience inadequate emergence (IE) characterized by unrest, restlessness, aggressiveness or in contrast sedation or lack of initiative. This may increase length of stay (LOS) and post-operative complications. The aim of this study was to investigate frequency, risk factors and consequences of IE. ⋯ One of 10 patients had IE as defined by the Nu-DESC score, which was significantly associated with increased LOS. Longer duration of anaesthesia, inhalational anaesthesia and ASA ≥3 were significantly associated to this.
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Acta Anaesthesiol Scand · Oct 2019
Age, SAPS 3 and female sex are associated with decisions to withdraw or withhold intensive care.
Intensive care treat critically ill patients. When intensive care is not considered beneficial for the patient, decisions to withdraw or withhold treatments are made. We aimed to identify independent patient variables that increase the odds for receiving a decision to withdraw or withhold intensive care. ⋯ Older age, higher SAPS 3 at admission and female sex were found to be independent variables that increased the odds to receive a decision to withdraw or withhold intensive care.
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Acta Anaesthesiol Scand · Oct 2019
Pre-medication before dental procedures: A randomized controlled study comparing intranasal dexmedetomidine with oral midazolam.
This study aimed to determine if intranasal dexmedetomidine is a superior pre-medication to oral midazolam in older, difficult children. ⋯ Intranasal dexmedetomidine provides higher success rate in sedation and parental separation compared to oral midazolam, in older, difficult children.
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Acta Anaesthesiol Scand · Oct 2019
Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol.
In the Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU) trial, 3291 adult ICU patients at risk for gastrointestinal (GI) bleeding were randomly allocated to intravenous pantoprazole 40 mg or placebo once daily in the ICU. No difference was observed between the groups in the primary outcome 90-day mortality or the secondary outcomes, except for clinically important gastrointestinal bleeding. However, heterogeneity of treatment effect (HTE) not detected by conventional subgroup analyses could be present. ⋯ NCT02467621.