Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 2025
Coagulation and platelet function in cold-stored whole blood on missions in a helicopter emergency service.
Haemorrhage is a leading cause of morbidity and mortality in trauma, and prehospital transfusion of blood products is often necessary. Whole blood has been proposed to be the best alternative, but it is unclear whether, and how, storage and transport of the blood in a helicopter affects the blood units. We investigated the coagulation capacity and platelet function in whole blood at different time points during helicopter missions. ⋯ Storage and transport of whole-blood units in a rescue helicopter, for up to 168 h, had a slight impact on the blood quality. Storage of whole blood on board of the helicopter holds up to European standard, measured as temperature and haemolysis.
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Acta Anaesthesiol Scand · Feb 2025
Locoregional anesthesia in patients with Brugada syndrome. A retrospective database analysis.
The use of local anesthetics (LA) in individuals with Brugada syndrome (BrS) remains a subject of debate due to the lack of large-scale studies confirming their potential risks. This study primarily aimed to evaluate the incidence of new malignant arrhythmias or defibrillation events in patients diagnosed with BrS during the perioperative period, following the administration of local anesthetics, and within 30 days postoperatively. The secondary objective was to analyze the occurrence of adverse effects during hospitalization, as well as 30-day readmission and mortality rates. ⋯ In this retrospective study, our findings do not indicate an increased arrhythmogenic risk or a higher incidence of adverse events associated with the administration of local anesthetics in patients with BrS. However, the available data are insufficient to confirm the safety of local anesthetic use in this population. Enhanced vigilance is recommended when administering local anesthetics to individuals with BrS. Prospective studies are necessary to further evaluate and establish the safety profile of local anesthetics in this patient group.
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Acta Anaesthesiol Scand · Feb 2025
First out-of-bed mobilisation in adults with severe acquired brain injury in Scandinavian neurointensive care units: A survey of current clinical practice (FOOBScan).
The harm-benefit balance for early out-of-bed mobilisation of patients with severe acquired brain injury (ABI) in neurointensive care units (neuro-ICUs) is unclear, and there are no clinical guidelines. This study aimed to survey the current clinical practice and perceptions among clinicians involved in first out-of-bed mobilisation in Scandinavian neuro-ICUs. ⋯ Mobilisation out of bed is frequently performed in patients with severe ABI in Scandinavian neuro-ICUs. The perceived clinical safety indicators for mobilisation were ICP, CPP, level of sedation, presence of vasospasms, and ABP.
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Acta Anaesthesiol Scand · Feb 2025
Observational StudyIssuing of albumin solutions to Danish public hospitals-A nationwide, retrospective, observational study based on pharmacy data from 2022.
Intravenous albumin is used for resuscitation and substitution but is not supported by high-certainty evidence. As clinical practice likely varies, we aimed to describe the issuing of albumin solutions across Danish public hospitals. ⋯ In this nationwide study on the issuing of albumin, we observed differences across regional, hospital, and departmental settings. Particularly, the proportional issuing of albumin solutions to ICUs and anaesthesia departments differed across geographical regions suggesting marked practice variation.